Processing of metacaspase into a cytoplasmic catalytic domain mediating cell death in Leishmania major
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چکیده
منابع مشابه
Processing of metacaspase into a cytoplasmic catalytic domain mediating cell death in Leishmania major
Metacaspases are cysteine peptidases that could play a role similar to caspases in the cell death programme of plants, fungi and protozoa. The human protozoan parasite Leishmania major expresses a single metacaspase (LmjMCA) harbouring a central domain with the catalytic dyad histidine and cysteine as found in caspases. In this study, we investigated the processing sites important for the matur...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2010
ISSN: 0950-382X
DOI: 10.1111/j.1365-2958.2010.07443.x